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April 2023

Volume 28Issue 3p53-118

Open Access

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Review Article

Using chemical and biological data to predict drug toxicity

Anika Liu,
Srijit Seal,
Hongbin Yang,
Andreas Bender

Published online: January 10, 2023

p53-64

Full Length Articles

High-throughput method to analyze the cytotoxicity of CAR-T Cells in a 3D tumor spheroid model using image cytometry

David Zurowski,
Samir Patel,
Daniel Hui,
...
Bo Lin,
Andrea Moore,
Leo Li-Ying Chan

Published online: February 07, 2023

p65-72

High-content phenotypic screen to identify small molecule enhancers of Parkin-dependent ubiquitination and mitophagy

Roberta Tufi,
Emily H. Clark,
Tamaki Hoshikawa,
...
Kunitoshi Takeda,
James M. Staddon,
Thomas Briston

Published online: January 03, 2023

p73-87

High throughput assay for compounds that boost BDNF expression in neurons

Guey-Ying Liao,
Haifei Xu,
Justin Shumate,
Louis Scampavia,
Timothy Spicer,
Baoji Xu

Published online: February 24, 2023

p88-94

High throughput screening for drugs that inhibit 3C-like protease in SARS-CoV-2

Emery Smith,
Meredith E. Davis-Gardner,
Ruben D. Garcia-Ordonez,
...
Patrick Griffin,
Michael Farzan,
Timothy P. Spicer

Published online: January 13, 2023

p95-101

High throughput screening of 0.5 million compounds against CRAF using Alpha CETSA^Ⓡ

Hannah Rowlands,
Kirsten Tschapalda,
Carolyn Blackett,
...
Martin Packer,
Laurence Arnold,
Geoffrey A. Holdgate

Published online: January 31, 2023

p102-110

Automated quality control tool for high-content imaging data by building 2D prediction intervals on reference biosignatures

Alemu Takele Assefa,
Bie Verbist,
Emmanuel Gustin,
Danielle Peeters

Published online: February 01, 2023

p111-117

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April 2023

Review Article

Using chemical and biological data to predict drug toxicity

Full Length Articles

High-throughput method to analyze the cytotoxicity of CAR-T Cells in a 3D tumor spheroid model using image cytometry

High-content phenotypic screen to identify small molecule enhancers of Parkin-dependent ubiquitination and mitophagy

High throughput assay for compounds that boost BDNF expression in neurons

High throughput screening for drugs that inhibit 3C-like protease in SARS-CoV-2

High throughput screening of 0.5 million compounds against CRAF using Alpha CETSA^Ⓡ

Automated quality control tool for high-content imaging data by building 2D prediction intervals on reference biosignatures

April 2023

Review Article

Using chemical and biological data to predict drug toxicity

Full Length Articles

High-throughput method to analyze the cytotoxicity of CAR-T Cells in a 3D tumor spheroid model using image cytometry

High-content phenotypic screen to identify small molecule enhancers of Parkin-dependent ubiquitination and mitophagy

High throughput assay for compounds that boost BDNF expression in neurons

High throughput screening for drugs that inhibit 3C-like protease in SARS-CoV-2

High throughput screening of 0.5 million compounds against CRAF using Alpha CETSAⓇ

Automated quality control tool for high-content imaging data by building 2D prediction intervals on reference biosignatures

High throughput screening of 0.5 million compounds against CRAF using Alpha CETSA^Ⓡ