Table of Contents page: SLAS Discovery

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Functional Genomics for Target Identification

Davide Gianni,
Stuart Farrow

Published in issue: July 2020

p531-534

Secretome-Based Screening in Target Discovery

Mei Ding,
Hanna Tegel,
Åsa Sivertsson,
...
Per-Erik Strömstedt,
Rick Davies,
Lovisa Holmberg Schiavone

Published in issue: July 2020

p535-551

CRISPR Meets Zebrafish: Accelerating the Discovery of New Therapeutic Targets

Davide Rubbini,
Carles Cornet,
Javier Terriente,
Vincenzo Di Donato

Published in issue: July 2020

p552-567

The New Frontier of Functional Genomics: From Chromatin Architecture and Noncoding RNAs to Therapeutic Targets

Natali Papanicolaou,
Alessandro Bonetti

Published in issue: July 2020

p568-580

Developing an Arrayed CRISPR-Cas9 Co-Culture Screen for Immuno-Oncology Target ID

Sarah Gee,
Nadine Nelson,
Aurelie Bornot,
...
Paul D. Smith,
Davide Gianni,
David J. Baker

Published in issue: July 2020

p581-590

A Whole Genome-Wide Arrayed CRISPR Screen in Primary Organ Fibroblasts to Identify Regulators of Kidney Fibrosis

Robert J. Turner,
Stefan Golz,
Carina Wollnik,
...
Ina Sternberger,
Uwe Andag,
Hauke Cornils

Published in issue: July 2020

p591-604

Arrayed CRISPR Screening Identifies Novel Targets That Enhance the Productive Delivery of mRNA by MC3-Based Lipid Nanoparticles

Douglas Ross-Thriepland,
Aurelie Bornot,
Larissa Butler,
...
Uchechukwu Odunze,
Beverley Isherwood,
Davide Gianni

Published in issue: July 2020

p605-617

A Novel Screening Approach for the Dissection of Cellular Regulatory Networks of NF-κB Using Arrayed CRISPR gRNA Libraries

Patrick O’Shea,
Jan Wildenhain,
Mathew Leveridge,
...
David Piper,
Jonathan Chesnut,
Beverley Isherwood

Published in issue: July 2020

p618-633

Combined siRNA and Small-Molecule Phenotypic Screening Identifies Targets Regulating Rhinovirus Replication in Primary Human Bronchial Epithelial Cells

Mei Ding,
Christian Tyrchan,
Elisabeth Bäck,
Jörgen Östling,
Steffen Schubert,
Christopher McCrae

Published in issue: July 2020

p634-645

Delivering Robust Candidates to the Drug Pipeline through Computational Analysis of Arrayed CRISPR Screens

Maria Luisa Guerriero,
Adam Corrigan,
Aurélie Bornot,
...
Patrick O’Shea,
Douglas Ross-Thriepland,
Samantha Peel

Published in issue: July 2020

p646-654

Combining Supervised and Unsupervised Machine Learning Methods for Phenotypic Functional Genomics Screening

Wienand A. Omta,
Roy G. van Heesbeen,
Ian Shen,
...
Marco René Spruit,
Matthieu J.S. Brinkhuis,
David A. Egan

Published in issue: July 2020

p655-664

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July 2020

Editorial

Functional Genomics for Target Identification

Reviews

Secretome-Based Screening in Target Discovery

CRISPR Meets Zebrafish: Accelerating the Discovery of New Therapeutic Targets

Perspective

The New Frontier of Functional Genomics: From Chromatin Architecture and Noncoding RNAs to Therapeutic Targets

Original Research

Developing an Arrayed CRISPR-Cas9 Co-Culture Screen for Immuno-Oncology Target ID

A Whole Genome-Wide Arrayed CRISPR Screen in Primary Organ Fibroblasts to Identify Regulators of Kidney Fibrosis

Arrayed CRISPR Screening Identifies Novel Targets That Enhance the Productive Delivery of mRNA by MC3-Based Lipid Nanoparticles

A Novel Screening Approach for the Dissection of Cellular Regulatory Networks of NF-κB Using Arrayed CRISPR gRNA Libraries

Combined siRNA and Small-Molecule Phenotypic Screening Identifies Targets Regulating Rhinovirus Replication in Primary Human Bronchial Epithelial Cells

Delivering Robust Candidates to the Drug Pipeline through Computational Analysis of Arrayed CRISPR Screens

Combining Supervised and Unsupervised Machine Learning Methods for Phenotypic Functional Genomics Screening