Table of Contents page: SLAS Discovery

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A KNIME-Based Analysis of the Zebrafish Photomotor Response Clusters the Phenotypes of 14 Classes of Neuroactive Molecules

Daniëlle Copmans,
Thorsten Meinl,
Christian Dietz,
...
Julia Ortmann,
Michael R. Berthold,
Peter A.M. de Witte

Published in issue: June 2016

p427-436

Discovery of Enhancers of the Secretion of Leukemia Inhibitory Factor for the Treatment of Multiple Sclerosis

Laura Vela,
Iván Caballero,
Leiping Fang,
...
Fernando Ramón,
Emilio Díez,
Maite de los Frailes

Published in issue: June 2016

p437-445

Discovery of Novel Inhibitors of the Tautomerase Activity of Macrophage Migration Inhibitory Factor (MIF)

Maria Cleofé Zapatero,
Paloma Pérez,
María Jesús Vázquez,
Gonzalo Colmenarejo,
Maite de los Frailes,
Fernando Ramón

Published in issue: June 2016

p446-458

At-Line Cellular Screening Methodology for Bioactives in Mixtures Targeting the α7-Nicotinic Acetylcholine Receptor

Reka A. Otvos,
Marija Mladic,
Gabriela Arias-Alpizar,
...
Govert W. Somsen,
August B. Smit,
Jeroen Kool

Published in issue: June 2016

p459-467

An Integrated Approach for Screening and Identification of Positive Allosteric Modulators of N-Methyl-D-Aspartate Receptors

Enrique Jambrina,
Rok Cerne,
Emery Smith,
...
Peter Gallagher,
Timothy P. Spicer,
Daniel Ursu

Published in issue: June 2016

p468-479

Kinetic Analysis of Membrane Potential Dye Response to Na_V1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against Na_V1.5

Michael Finley,
Jason Cassaday,
Tony Kreamer,
...
Wei Lemaire,
Donnette Staas,
Jixin Wang

Published in issue: June 2016

p480-489

Development of an HTRF Assay for the Detection and Characterization of Inhibitors of Catechol-O-Methyltransferase

Martha Kimos,
Maggi Burton,
David Urbain,
...
Michel Gillard,
James Barrow,
Martyn Wood

Published in issue: June 2016

p490-495

Characterization of Differentiated SH-SY5Y as Neuronal Screening Model Reveals Increased Oxidative Vulnerability

J.I. Forster,
S. Köglsberger,
C. Trefois,
...
L. Buck,
R. Balling,
P.M.A. Antony

Published in issue: June 2016

p496-509

Characterization of Early Cortical Neural Network Development in Multiwell Microelectrode Array Plates

Ellese Cotterill,
Diana Hall,
Kathleen Wallace,
William R. Mundy,
Stephen J. Eglen,
Timothy J. Shafer

Published in issue: June 2016

p510-519

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June 2016

Editorial

JBS Special Issue: Innovative Screening Methodologies to Identify New Compounds for the Treatment of Central Nervous System Disorders

Original Research

A KNIME-Based Analysis of the Zebrafish Photomotor Response Clusters the Phenotypes of 14 Classes of Neuroactive Molecules

Discovery of Enhancers of the Secretion of Leukemia Inhibitory Factor for the Treatment of Multiple Sclerosis

Discovery of Novel Inhibitors of the Tautomerase Activity of Macrophage Migration Inhibitory Factor (MIF)

At-Line Cellular Screening Methodology for Bioactives in Mixtures Targeting the α7-Nicotinic Acetylcholine Receptor

An Integrated Approach for Screening and Identification of Positive Allosteric Modulators of N-Methyl-D-Aspartate Receptors

Kinetic Analysis of Membrane Potential Dye Response to Na_V1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against Na_V1.5

Development of an HTRF Assay for the Detection and Characterization of Inhibitors of Catechol-O-Methyltransferase

Characterization of Differentiated SH-SY5Y as Neuronal Screening Model Reveals Increased Oxidative Vulnerability

Characterization of Early Cortical Neural Network Development in Multiwell Microelectrode Array Plates